Home | RSS

Links
Parenting Guide
WebMD Health Information
Health and Biology

Lupus Symptoms in Women

Jul 25, 2011 > Various
Are you looking for Lupus Symptoms in Women? Lupus is a clinical syndrome, the cause of which remains uncertain. It is a member of the family of autoimmune rheumatic diseases. Lupus is more common in women, and certainly more common amongst the black and Chinese population. Itís clinical diversity is at least apparently matched by its serological diversity. The prevalence of lupus among Afro-Caribbeans is approximately five times that of a Caucasian population, and about 2 Ĺ times that of an Asian population.

Lupus Symptoms in Women

Lupus is far from confined to the skin. Indeed, we now recognize lupus in all its many systemic forms, much of the work being done in this century in various parts of the United States. At least 10% of the patients in my cohort who have been misdiagnoses as suffering from lymphomas or other malignant diseases. Virtually all lupus patients of course have musculoskeletal involvement, substantial number have dermatologic involvement, and a large number of patients also have gastrointestinal disease. Perhaps nowhere is the clinical diversity shown that in the cerebral system, where anything from migraine to madness may be a feature of lupus. About 30% of patients with lupus presenting to a rheumatologist will turn out to have significant renal disease. Perhaps 40% will have cardiopulmonary disease and virtually all patients with lupus have some hematological manifestation or another.

Lupus Symptoms in Women For the final clinical conundrum, Iíd like to draw your attention to thrombocytopenia. Iíd like to persuade you, at least to my mind, that there are at least three sorts of thrombocytopenia in patients with lupus. There are a group of patients who present with what is generally regarded as idiopathic disease, idiopathic thrombocytopenia, until other features of lupus turn up some years later. The platelet count can certainly get very low with these patients and clinical symptoms referable to thrombocytopenia are very common. In addition I recognize a group of patients with what I call chronic persistent thrombocytopenia within the context of lupus. The platelet count here often runs between 50 and 125, but the clinical symptoms referable to this platelet count are much rarer. There are a similar number of patients who have a dramatic fall in their platelet counts. This can occur over a matter of weeks or months and there are again frequent clinical features relevant to the platelet counts. How best to treat these patients? This is a review of a number of patients with lupus or the antiphospholipid syndrome, reviewed by _ and myself some years ago. In our cohort 16.5% of patients had thrombocytopenia as judged by a platelet count of less than 100; 7.5% of these patients had thrombocytopenia linked to antiphospholipid antibodies and 6% have very severe thrombocytopenia, counts less than 15 with symptoms.

Lupus Symptoms

If each of the eight organ systems, based largely on clinical questions - and I stress that, clinical questions - we define disease activity on this A-E basis. Where A represents action. The patient is severely ill, has sufficiently severe clinical features that they require major immunosuppressive therapy. B for beware, in the sense that we already knew the patient was active. C for contentment. There is low level activity, not requiring much in the way of therapy. D for discount, in the sense that the disease was once active but is no longer active. And E for no evidence of disease in the system now or previously. Hereís an example of the way that this works. Take, for example, the cardiovascular assessment. In a patient who presents with cardiac failure or symptomatic effusion and two of these other features listed here, from pleuropericardial pain due to friction rub, to deteriorating lung function. That patient will be categorized for their cardiovascular assessment as an A. In contrast, if only two of these criteria were present, they would be categorized as a B. If only one criteria or mild chest pain was present, they would get a C. A D if there was previous involvement but none current, and E for no previous involvement.

Now all of these patients were treated initially with large doses of corticosteroids and a significant number of them failed to respond. What should you do then? There is some conflicting data in the literature but we have found that splenectomy done relatively early to be a very helpful way of proceeding. So, of 17 patients that we identified during this time period, 12 had lupus, four had antiphospholipid syndrome, and one had three features of lupus and what we referred to as lupus-like. Nine of these patients were eventually given a splenectomy. Six of them responded completely, two of them gave a partial response, which unfortunately was not sustained, and one patient died of an unrelated carcinoma. The patient with the lupus-like disease also did extremely well. So for us, we tend to treat patients with thrombocytopenia, especially the acutely presenting ones, with corticosteroids. If that doesnít work within a few months we would proceed to splenectomy. We may use some IV Ig on the way.

That's some stuff about Lupus Symptoms in Women


Other Articles

Lupus Symptoms in Women #0Allergy In Children
The importance of an early diagnosis of allergy cannot be overemphasized. This diagnosis should be made in infancy or early childhood. This involves not only recognition that the condition affecting the child is allergic, but also a serious attempt at discovering the cause of the allergy. In doing this, however, one meets frequently with great deal of resistance by the mother because she does not want to see the child hurt, r because she somehow has a vague suspicion that skin testing endangers the child's health. The mother must understand the importance of such an early diagnosis. She must realize that delay is equivalent to neglect, and that neglect needlessly expose the child to the dangers of complications which may result from an untreated allergy a case of hay fever or case of asthma in a child. After a few years, however, this condition becomes complicated by nasal infection or by bronchitis, or by changes in the tissues of the lungs. These changes become refractory to treatment, so that even if the allergy is discovered, treatment of complications becomes difficult if not impossible. The mother must also understand that skin testing, if properly done, is not dangerous and does not affect the child's physical condition.
Lupus Symptoms in Women #1Hiatus Hernia Treatment
The term hiatus hernia describes diaphragmatic hernia or weakness in the diaphragm, the horizontal muscular wall separating the organs of the chest from the organs of the abdomen. A hernia is an abnormal protrusion of an organ or tissue through an opening. A hiatus, or opening, permits the esophagus to carry food from the mouth to the stomach. Blood vessels and nerves also pass through the diaphragm. The diaphragm is an important group of muscles for contracting and expanding the lungs, forcing air in and out of the lung tissues.
Lupus Symptoms in Women #2Calculate bmi for teenage girls
Calculate Your Body Mass Index Body mass index (BMI) is a measure of body fat based on height and weight that applies to adult men and women.
Lupus Symptoms in Women #3Antioxidant vitamins
Three vitamins are classified as antioxidants Ė vitamins C, E, and beta-carotene. Antioxidants are protective substances because they help neutralize the activity of free radicals. Free radicals are naturally produced chemicals that arise from normal cell activity. When ever the body uses oxygen or is exposed o a toxin, such as cigarette smoke, it forms free radicals. These unstable chemicals can damage cells throughout the body. They may damage a cell's DNA in ways that lead to cancer, may interact with cholesterol in the bloodstream and form oxidized Low-density lipoprotein (LDL) may cause cataracts and rheumatoid arthritis, and may be factor in the physiological changes associated with the aging process. Anything that interferes with the destructive effects of free radicals offers a health advantage. Vitamins C, E, and beta-carotene are believed to prevent the oxidation of cholesterol and other molecules linked to the diseases mentioned previously, most notably heart disease and cancer. A common cooking practice illustrates this antioxidant effect: some foods like bananas, peaches, apples, and potatoes quickly turn brown when exposed to air. However, when such foods are dipped in lemon or orange juice, the vitamin C in the juice acts as an antioxidant and prevents browning.
Lupus Symptoms in Women #4Heart Failure Physical Examination
Your medical history includes anything about your past and present health-conditions you used to have or conditions you have now. Tell your doctor about medical problems of any type, including any surgery that you have had. When giving your doctor your medical history, be complete and detailed in your descriptions. Even if an illness is completely gone or does not seem important to you, knowing about that problem may help your doctor diagnose heart failure. Also, knowing all of your past and present medical problems will help your doctor decide the best way to care for your condition.
Lupus Symptoms in Women #5Hypomanic Symptoms in Children and Treatment
Hypomania (literally, "below mania" ) is a mood state characterized by persistent and pervasive elevated (euphoric) or irritable mood, as well as thoughts and behaviors that are consistent with such a mood state.
Lupus Symptoms in Women #6Cymothoa Exigua in Human and Life Cycle
Cymothoa exigua is a tiny crustacean that sneaks up on a fish (specifically, a red snapper) and works its way in through the gills. Typical parasite behavior so far. Then it attaches itself to the base of the fish's tongue, the tongue evidently being the tastiest part of the fish (get it!?). The parasite uses its claws to dig into the tongue and drink the fish's blood--and that's just the beginning
Lupus Symptoms in Women #7HCG diet shots
Are you looking for HCG diet shots? Effect of human chorionic gonadotrophin on weight loss, hunger, and feeling of well-beingW. L. Asher, M.D.1 and Harold W. Harper, M.D.11.From the American Society of Bariatric Physicians Research Council, 333 West Hampden Avenue, Englewood, Colorado 80110. Twenty female patients on 500 to 550 kcal diets receiving daily injections of 125 IU of human chorionic gonadotrophin (HCG) were compared with 20 female patients on 500 to 550 kcal diets receiving placebo injections. Patients in both groups were instructed to return for daily injections 6 days each week for a total of 36 injections (unless desired weight was achieved prior to this).
Lupus Symptoms in Women #8Types of Blood Cancer Symptoms and Treatments
Overview of Blood Cancer The major forms of blood cancer are lymphoma, leukemia and multiple myeloma. These cancers are formed either in the bone marrow or the lymphatic tissues of the body. They affect the way your body makes blood and provides immunity from other diseases.
Lupus Symptoms in Women #9Clozapine Side Effects Management
Clozapine (sold as Clozaril, Azaleptin, Leponex, Fazaclo, Froidir; Denzapine, Zaponex in the UK; Klozapol in Poland, Clopine in Australia and New Zealand) is an antipsychotic medication used in the treatment of schizophrenia, and is also used off-label in the treatment of bipolar disorder. Wyatt. R and Chew. R (2005) tells us there are three pharmaceutical companies that market this drug at present: Novartis Pharmaceuticals (manufacturer), Mylan Laboratories and Ivax Pharmaceuticals (market generic clozapine). The first of the atypical antipsychotics to be developed, it was first introduced in Europe in 1971, but was voluntarily withdrawn by the manufacturer in 1975 after it was shown to cause agranulocytosis, a condition involving a dangerous decrease in the number of white blood cells, that led to death in some patients. In 1989, after studies demonstrated that it was more effective than any other antipsychotic for treating schizophrenia[citation needed], the U.S. Food and Drug Administration (FDA) approved clozapine's use but only for treatment-resistant schizophrenia.
Lupus Symptoms in Women #10Amenorrhea Causes Medicine Treatment and Pregnancy
Amenorrhea may be associated with infertility, endometrial hyperplasia, or osteopenia. It may be the presenting sign of an underlying metabolic, endocrine, congenital, or gynecologic disorder.
Lupus Symptoms in Women #11How is an endometrial biopsy done
An endometrial biopsy is often done in the doctorís office, usually without anesthesia. Although the procedure is quickly accomplished, it is painful. If a physical does not have nitrous oxide available in his or her office, the patient can be given strong pain pills to use before coming to the office. A paracervical block can be also be used.
Lupus Symptoms in Women #12Immunization for children and schedule
You can see the diseases, vaccine-preventable diseases in this column and the number of cases reported prior to routine immunization and then the number of cases reported last year in this country. Youíll see a real dramatic decline in these vaccine-preventable diseases. Between 95 and 100% decline and this is due to routine immunization against these diseases. So this is a very dramatic success story, and because of this - this is from the MMWR published by the CDC - the top public health achievement of this century in this country is routine vaccination. So you can be assured that this is something that will be on the Boards because itís been such a tremendous success, a tremendous achievement and it is very important.

Copyright (c) 2011 by DRZ
Privacy Policy | Contact Us