Are you looking for Lupus Symptoms in Women? Lupus is a clinical syndrome, the cause of which remains uncertain. It is a member of the family of autoimmune rheumatic diseases. Lupus is more common in women, and certainly more common amongst the black and Chinese population. Itís clinical diversity is at least apparently matched by its serological diversity. The prevalence of lupus among Afro-Caribbeans is approximately five times that of a Caucasian population, and about 2 Ĺ times that of an Asian population.
Lupus Symptoms in Women
Lupus is far from confined to the skin. Indeed, we now recognize lupus in all its many systemic forms, much of the work being done in this century in various parts of the United States. At least 10% of the patients in my cohort who have been misdiagnoses as suffering from lymphomas or other malignant diseases. Virtually all lupus patients of course have musculoskeletal involvement, substantial number have dermatologic involvement, and a large number of patients also have gastrointestinal disease. Perhaps nowhere is the clinical diversity shown that in the cerebral system, where anything from migraine to madness may be a feature of lupus. About 30% of patients with lupus presenting to a rheumatologist will turn out to have significant renal disease. Perhaps 40% will have cardiopulmonary disease and virtually all patients with lupus have some hematological manifestation or another.
For the final clinical conundrum, Iíd like to draw your attention to thrombocytopenia. Iíd like to persuade you, at least to my mind, that there are at least three sorts of thrombocytopenia in patients with lupus. There are a group of patients who present with what is generally regarded as idiopathic disease, idiopathic thrombocytopenia, until other features of lupus turn up some years later. The platelet count can certainly get very low with these patients and clinical symptoms referable to thrombocytopenia are very common. In addition I recognize a group of patients with what I call chronic persistent thrombocytopenia within the context of lupus. The platelet count here often runs between 50 and 125, but the clinical symptoms referable to this platelet count are much rarer. There are a similar number of patients who have a dramatic fall in their platelet counts. This can occur over a matter of weeks or months and there are again frequent clinical features relevant to the platelet counts. How best to treat these patients? This is a review of a number of patients with lupus or the antiphospholipid syndrome, reviewed by _ and myself some years ago. In our cohort 16.5% of patients had thrombocytopenia as judged by a platelet count of less than 100; 7.5% of these patients had thrombocytopenia linked to antiphospholipid antibodies and 6% have very severe thrombocytopenia, counts less than 15 with symptoms.
If each of the eight organ systems, based largely on clinical questions - and I stress that, clinical questions - we define disease activity on this A-E basis. Where A represents action. The patient is severely ill, has sufficiently severe clinical features that they require major immunosuppressive therapy. B for beware, in the sense that we already knew the patient was active. C for contentment. There is low level activity, not requiring much in the way of therapy. D for discount, in the sense that the disease was once active but is no longer active. And E for no evidence of disease in the system now or previously. Hereís an example of the way that this works. Take, for example, the cardiovascular assessment. In a patient who presents with cardiac failure or symptomatic effusion and two of these other features listed here, from pleuropericardial pain due to friction rub, to deteriorating lung function. That patient will be categorized for their cardiovascular assessment as an A. In contrast, if only two of these criteria were present, they would be categorized as a B. If only one criteria or mild chest pain was present, they would get a C. A D if there was previous involvement but none current, and E for no previous involvement.
Now all of these patients were treated initially with large doses of corticosteroids and a significant number of them failed to respond. What should you do then? There is some conflicting data in the literature but we have found that splenectomy done relatively early to be a very helpful way of proceeding. So, of 17 patients that we identified during this time period, 12 had lupus, four had antiphospholipid syndrome, and one had three features of lupus and what we referred to as lupus-like. Nine of these patients were eventually given a splenectomy. Six of them responded completely, two of them gave a partial response, which unfortunately was not sustained, and one patient died of an unrelated carcinoma. The patient with the lupus-like disease also did extremely well. So for us, we tend to treat patients with thrombocytopenia, especially the acutely presenting ones, with corticosteroids. If that doesnít work within a few months we would proceed to splenectomy. We may use some IV Ig on the way.
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Symptoms of meningitis in adults Are you looking for symptoms of meningitis in adults?
Meningitis is inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges. The inflammation may be caused by infection with viruses, bacteria, or other microorganisms, and less commonly by certain drugs. Meningitis can be life-threatening because of the inflammation's proximity to the brain and spinal cord; therefore the condition is classified as a medical emergency.
Many of the bacteria and viruses that cause meningitis are fairly common and associated with other routine illnesses. Bacteria and viruses that infect the skin, urinary system, gastrointestinal or respiratory tract can spread by the bloodstream to the meninges through cerebrospinal fluid, the fluid that circulates in and around the spinal cord.
Bipolar Disorder Symptoms Bipolar I disorder typically begins in the teenage years, the 20s, or the 30s. The first episode could be manic, depressive, or mixed. One common mode of onset is mild retarded depression, or hypersomnia, for a few weeks or months, which then switches into a manic episode.
HCG diet shots Are you looking for HCG diet shots? Effect of human chorionic gonadotrophin on weight loss, hunger, and feeling of well-beingW. L. Asher, M.D.1 and Harold W. Harper, M.D.11.From the American Society of Bariatric Physicians Research Council, 333 West Hampden Avenue, Englewood, Colorado 80110.
Twenty female patients on 500 to 550 kcal diets receiving daily injections of 125 IU of human chorionic gonadotrophin (HCG) were compared with 20 female patients on 500 to 550 kcal diets receiving placebo injections. Patients in both groups were instructed to return for daily injections 6 days each week for a total of 36 injections (unless desired weight was achieved prior to this).
What is oxycodone and the side effects What is oxycodone? and what are oxycodone side effects? Oxycodone (OxyContin and other brand names) is an opioid analgesic medication synthesized from opium-derived thebaine. It was developed in 1916 in Germany, as one of several new semi-synthetic opioids in an attempt to improve on the existing opioids: morphine, diacetylmorphine (heroin), and codeine.
Glaucoma Treatment Guidelines Are you looking for glaucoma treatment guidelines? Glaucoma is an eye disorder in which the optic nerve suffers damage, permanently damaging vision in the affected eye(s) and progressing to complete blindness if untreated. It is often, but not always, associated with increased pressure of the fluid in the eye (aqueous humour). The term 'ocular hypertension' is used for cases having constantly raised intraocular pressure (IOP) without any associated optic nerve damage. Conversely, the term 'normal' or 'low tension glaucoma' is suggested for the typical visual field defects when associated with a normal or low IOP.
Lupus Symptoms in Women Are you looking for Lupus Symptoms in Women? Lupus is a clinical syndrome, the cause of which remains uncertain. It is a member of the family of autoimmune rheumatic diseases. Lupus is more common in women, and certainly more common amongst the black and Chinese population. Itís clinical diversity is at least apparently matched by its serological diversity. The prevalence of lupus among Afro-Caribbeans is approximately five times that of a Caucasian population, and about 2 Ĺ times that of an Asian population.
Tips for Getting Pregnant You have been married for years? but have not had children. Maybe it helps you practice the following tips for couples to get pregnant.
Trigeminal Neuralgia Treatment Guidelines Are you looking for trigeminal neuralgia treatment guidelines? Trigeminal neuralgia (TN), tic douloureux (also known as prosopalgia, the Suicide Disease or Fothergill's disease) is a neuropathic disorder characterized by episodes of intense pain in the face, originating from the trigeminal nerve. It has been described as among the most painful conditions known. It is estimated that 1 in 15,000 people suffer from TN, although the actual figure may be significantly higher due to frequent misdiagnosis. In a majority of cases, TN symptoms begin appearing after the age of 50, although there have been cases with patients being as young as three years of age. It is more common in females than males.
Plant based diet recipes and book Are you looking for plant based diet recipes and book? Perhaps you read Rip Esselstyn's The Engine 2 Diet or Jonathan Safran Foerís Eating Animals and want to reduce your risk of lifestyle related diseases and avoid factory farms, or perhaps it's the recent U.N. study that said eating less meat is better for the planet - either way, thereís no doubt that reducing your meat intake and embracing a plant-based diet is one of the best things you can do for your health and the environment.
Arteries of the Body Function and Pictures Arteries facts
Arteries are vessels that conduct blood away from the heart
Arteries transport oxygenated blood under pressure to the cells of the
body. (The pulmonary artery is an exception; it transports deoxygenated blood
to the lungs)
The arterial wall consists of three primary layers:
The innermost layer consists of simple squamous epithelium (the endothelium)
surrounded by a connective tissue basement membrane with elastic fibers.The
middle layer consists mainly of smooth muscle and is usually the thickest layer.
It not only provide support for the vessel but also changes vessel
diameter to regulate blood flow and blood pressure.The outermost layer,
which attaches the vessel to the surrounding tissue, consists of connective
tissue with varying amounts of elastic and collagen fibers.
What is a Low Glycemic Diet A recent Harvard study found that a low-glycemic diet was the best of three popular diets at both maintaining metabolism during weight loss and maintaining cardiovascular health. But what is it and what are low glycemic foods anyway?
The diet, which is also known as the glycemic index diet or GI diet, emphasizes unprocessed foods, complex carbs and food combining. It was originally developed as a diet to help diabetes patients regulate their blood sugar and, according to WebMD, is still most effective in this capacity. Many popular diets, including Nutrisystem, the Zone diet, Sugar Busters and South Beach diet incorporate low-glycemic principles.
New Treatments for Arrhythmias in Children This is a general outline of the approach to arrhythmias. The first thing you are going to do is; what is the heart rate? Fast, slow? Is it regular, irregular? The next thing you will notice is; is it wide or narrow QRS, because obviously you will be worried about how dangerous this might be. And then you will probably start to look a little more closely and see if you see P waves. And the P waves are whatís going to really give you a diagnosis. They can be absent, they can be normal, they might be retrograde or they might be intermittent or multiple. Whenever possible, itís very helpful to obtain 12-lead EKGs to diagnose a rhythm disorder. Obviously if the patient is unstable itís not worth it, in a pulseless patient. But if a patient is stable talking to you, itís very helpful to figure out what this was and how to treat it long-term, if you have 12-lead EKGs. Itís also very helpful to run rhythm strips, preferably rhythm strips out of an EKG machine that will give you three leads rather than something off of a defibrillator or monitor during interventions when you give adenosine, even vagal maneuvers.
Radiation Safety Principles and Standard
The International Commission on Radiological Protection (ICRP) has
proposed that following principles should guide the use of ionizing
radiation safety standard:
No practice involving exposures to radiation should be adopted unless it
produces sufficient benefit to the exposed individuals or society to offset
the radiation detriment it causes (the justification of practice)
In relation to any particular source within a practice, the magnitude of
individuals doses, the number of people exposed, and the likelihood on
incurring exposures where these are not certain to be received should all kept
as low as reasonably achievable (ALARA), economic and social factors being
taken into account. This procedure should be constrained by restrictions of
the doses to individuals (dose constraint), so as to limit the inequity likely
to result from the inherent economic and social judgments.
The exposure of individuals resulting from the combination of all the
relevant practices should be subject to dose limits, or to some control of
risk in the case of potential exposures. These are aimed at ensuring that no
individual is exposed radiation risks that are judged to be unacceptable from
these practices in any normal circumstances. Not all sources are susceptible
of control by action at the source and it is necessary to specify the sources
to be included as relevant before selecting a dose limit.