Are you looking for Lupus Symptoms in Women? Lupus is a clinical syndrome, the cause of which remains uncertain. It is a member of the family of autoimmune rheumatic diseases. Lupus is more common in women, and certainly more common amongst the black and Chinese population. It’s clinical diversity is at least apparently matched by its serological diversity. The prevalence of lupus among Afro-Caribbeans is approximately five times that of a Caucasian population, and about 2 ½ times that of an Asian population.
Lupus Symptoms in Women
Lupus is far from confined to the skin. Indeed, we now recognize lupus in all its many systemic forms, much of the work being done in this century in various parts of the United States. At least 10% of the patients in my cohort who have been misdiagnoses as suffering from lymphomas or other malignant diseases. Virtually all lupus patients of course have musculoskeletal involvement, substantial number have dermatologic involvement, and a large number of patients also have gastrointestinal disease. Perhaps nowhere is the clinical diversity shown that in the cerebral system, where anything from migraine to madness may be a feature of lupus. About 30% of patients with lupus presenting to a rheumatologist will turn out to have significant renal disease. Perhaps 40% will have cardiopulmonary disease and virtually all patients with lupus have some hematological manifestation or another.
For the final clinical conundrum, I’d like to draw your attention to thrombocytopenia. I’d like to persuade you, at least to my mind, that there are at least three sorts of thrombocytopenia in patients with lupus. There are a group of patients who present with what is generally regarded as idiopathic disease, idiopathic thrombocytopenia, until other features of lupus turn up some years later. The platelet count can certainly get very low with these patients and clinical symptoms referable to thrombocytopenia are very common. In addition I recognize a group of patients with what I call chronic persistent thrombocytopenia within the context of lupus. The platelet count here often runs between 50 and 125, but the clinical symptoms referable to this platelet count are much rarer. There are a similar number of patients who have a dramatic fall in their platelet counts. This can occur over a matter of weeks or months and there are again frequent clinical features relevant to the platelet counts. How best to treat these patients? This is a review of a number of patients with lupus or the antiphospholipid syndrome, reviewed by _ and myself some years ago. In our cohort 16.5% of patients had thrombocytopenia as judged by a platelet count of less than 100; 7.5% of these patients had thrombocytopenia linked to antiphospholipid antibodies and 6% have very severe thrombocytopenia, counts less than 15 with symptoms.
If each of the eight organ systems, based largely on clinical questions - and I stress that, clinical questions - we define disease activity on this A-E basis. Where A represents action. The patient is severely ill, has sufficiently severe clinical features that they require major immunosuppressive therapy. B for beware, in the sense that we already knew the patient was active. C for contentment. There is low level activity, not requiring much in the way of therapy. D for discount, in the sense that the disease was once active but is no longer active. And E for no evidence of disease in the system now or previously. Here’s an example of the way that this works. Take, for example, the cardiovascular assessment. In a patient who presents with cardiac failure or symptomatic effusion and two of these other features listed here, from pleuropericardial pain due to friction rub, to deteriorating lung function. That patient will be categorized for their cardiovascular assessment as an A. In contrast, if only two of these criteria were present, they would be categorized as a B. If only one criteria or mild chest pain was present, they would get a C. A D if there was previous involvement but none current, and E for no previous involvement.
Now all of these patients were treated initially with large doses of corticosteroids and a significant number of them failed to respond. What should you do then? There is some conflicting data in the literature but we have found that splenectomy done relatively early to be a very helpful way of proceeding. So, of 17 patients that we identified during this time period, 12 had lupus, four had antiphospholipid syndrome, and one had three features of lupus and what we referred to as lupus-like. Nine of these patients were eventually given a splenectomy. Six of them responded completely, two of them gave a partial response, which unfortunately was not sustained, and one patient died of an unrelated carcinoma. The patient with the lupus-like disease also did extremely well. So for us, we tend to treat patients with thrombocytopenia, especially the acutely presenting ones, with corticosteroids. If that doesn’t work within a few months we would proceed to splenectomy. We may use some IV Ig on the way.
That's some stuff about Lupus Symptoms in Women
Best countries for Plastic Surgery Are you looking for Best countries for plastic surgery?
Cosmetic plastic surgery includes surgical and nonsurgical procedures that reshape normal structures of the body in order to improve appearance and self-esteem. Healthy individuals with a positive outlook and realistic expectations are appropriate candidates for cosmetic procedures. Plastic surgery is a personal choice and should be done for yourself, not to fulfill someone else's desires or to try to fit an ideal image. Because it is elective, cosmetic surgery is usually not covered by health insurance.
Ornish diet recipes and meal plan Are you looking for Ornish diet recipes and meal plan? Unlike other diet books that make big promises, Eat More, Weigh Less, by Dean Ornish, MD, soft-pedals the health claims for this diet for the masses, adapted from his regimen to reverse heart disease. Ornish is well known in the medical community because of his success in reversing blockages to the heart, once thought impossible without surgery or drugs. Ornish also runs his own health and diet site here at WebMD which can give you additional details about his plan.
Radiation Safety Principles and Standard
The International Commission on Radiological Protection (ICRP) has
proposed that following principles should guide the use of ionizing
radiation safety standard:
No practice involving exposures to radiation should be adopted unless it
produces sufficient benefit to the exposed individuals or society to offset
the radiation detriment it causes (the justification of practice)
In relation to any particular source within a practice, the magnitude of
individuals doses, the number of people exposed, and the likelihood on
incurring exposures where these are not certain to be received should all kept
as low as reasonably achievable (ALARA), economic and social factors being
taken into account. This procedure should be constrained by restrictions of
the doses to individuals (dose constraint), so as to limit the inequity likely
to result from the inherent economic and social judgments.
The exposure of individuals resulting from the combination of all the
relevant practices should be subject to dose limits, or to some control of
risk in the case of potential exposures. These are aimed at ensuring that no
individual is exposed radiation risks that are judged to be unacceptable from
these practices in any normal circumstances. Not all sources are susceptible
of control by action at the source and it is necessary to specify the sources
to be included as relevant before selecting a dose limit.
Stages and Effects of Pyrexia and Hyperpyrexia A pyrexia is a body temperature between 37.60 and 400C and hyperpyrexia is a temperature > 400C. They are conditions in which the thermoregulatory mechanisms are intact but the body temperature is high. Infection s the most common cause of pyrexia and sepsis of hyperpyrexia but there are other causes. A number of drugs have been associated with pyrexia, e.g. diuretics, antiseizure therapy, analgesics, antiarrhythmics and antibiotics. Other causes of pyrexia include neoplasm, surgery, acute myocardial infarctions, heart failure, haemolysis (seen in reactions to blood transfusions) and hyperthyroidism.
Managing Stress Behaviors Stress is not something that you can run from or wish into nonexistence. To control stress, you must meet it head on and use as many resources as you can to insure that your coping skills are fine-tuned and ready to help you. In planning your personal strategy for stress success, you should consider the following :
Glucosamine Side Effects in Humans and Dosage Glucosamine (C6H13NO5) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Glucosamine is part of the structure of the polysaccharides chitosan and chitin, which compose the exoskeletons of crustaceans and other arthropods, cell walls in fungi and many higher organisms. Glucosamine is one of the most abundant monosaccharides. It is produced commercially by the hydrolysis of crustacean exoskeletons or, less commonly by fermentation of a grain such as corn or wheat. In the US it is one of the most common non-vitamin, non-mineral, dietary supplements used by adults.
Treatment of heart failure due to systolic dysfunction A. Treatment of the underlying cardiac disease
Hypertension is the primary cause of HF in many patients.
Angiotensin converting enzyme (ACE) inhibitors, beta
blockers, and angiotensin II receptor blockers (ARBs) are
the preferred antihypertensive agents because they improve
survival in HF. Beta blockers can also provide anginal relief
in ischemic heart disease and rate control in with atrial
Renovascular disease. Testing for renovascular disease is
indicated if there is severe or refractory hypertension, a
sudden rise in blood pressure, or repeated episodes of flash
Ischemic heart disease. Coronary atherosclerosis is the
most common cause of cardiomyopathy, comprising 50 to
75 percent of patients with HF.
a. All patients with documented ischemic heart disease
should be treated medically for relief of angina and with
risk factor reduction, such as control of serum lipids.
b. Myocardial revascularization with angioplasty or bypass
surgery may improve exercise capacity and prognosis in
patients with hibernating myocardium. Revascularization
should also be considered for repeated episodes of acute
left ventricular dysfunction and flash pulmonary edema.
Valvular disease is the primary cause of HF 10 to 12 percent.
Other causes of heart failure: Alcohol abuse, cocaine
abuse, obstructive sleep apnea, nutritional deficiencies,
myocarditis, hemochromatosis, sarcoidosis, thyroid disease,
and rheumatologic disorders such as systemic lupus
Best cold medicine for adult What is the Best cold medicine for adult?
Cold medicine can be a help and a hindrance in our lives when we are sick. Though it won't cure your cold or flu, it can improve your symptoms. But it also can have side effects. Also, which one do you choose? It can be quite confusing. Here you will find out about different cold medicines, how they work, examples of different products in each category and what they are used for.
Over the counter ringworm treatment for kids Are you looking for over the counter ringworm treatment for kids? What will you do if you see red itchy patches on your body? It may be a case of ring worm infection. It may sound bad, but it can be cured easily with over-the-counter ringworm treatment.
Ringworm is a common skin infection caused by a fungus. The fungi feeds on the dead cells of skin and hair causing a ring of irritated itchy skin that looks like a worm. This may cause a rash and becomes sore. It may appear as scalp ring worm, body ringworm, face ring worm or groin ringworm.
Prescription diet pills list and review Prescription diet pills aren't for the person who wants to shed a few pounds to fit into a holiday party dress or tuxedo. Only people who are "obese" (those who are 30 percent over their ideal weight, or have a Body Mass Index (BMI) of 30 or more - see National Heart, Lung and Blood Institute: Healthy Weight to calculate your BMI) or who have a history of high blood pressure or diabetes are good candidates for prescription diet medications, according to the National Institutes of Health (NIH).
HCG Diet Plan Phase 1 Are you looking for HCG Diet Plan Phase 1? The Homeopathic HCG diet plan does not need to be mixed. Drops are taken 3 times per day, typically preceding breakfast, lunch and dinner. Do not eat or drink anything 15 minutes before or after taking HCG drops. Using the oral syringe provided, drop .38 ml of HCG under your tongue and hold for at least 15 seconds before swallowing. Keep dropper very clean. You can carry your HCG drops and HCG diet plan with you throughout the day, but it's best to keep it in a cool, dark place. If you're at home, the fridge is best. Note: taking more than the recommended dosage from the HCG diet plan could result in depleting of drops before the 26 or 40 days are finished.
Holoprosencephaly prognosis and pictures What is Holoprosencephaly definition? Holoprosencephaly (HPE, once known as arhinencephaly) is a cephalic disorder in which the prosencephalon (the forebrain of the embryo) fails to develop into two hemispheres. Normally, the forebrain is formed and the face begins to develop in the fifth and sixth weeks of human pregnancy. Hox genes, which guide placement of embryonic structures, fail to activate along the midline of the head, allowing structures that are normally paired on the left and right to merge. The condition also occurs in other species, as with Cy, the Cyclops kitten.
The condition can be mild or severe. According to the National Institute of Neurological Disorders and Stroke (NINDS), "in most cases of holoprosencephaly, the malformations are so severe that babies die before birth.
New Treatments for Epididymitis The epididymis is located along the posterior border of the testicle with the head. Epididymitis is an inflammation of the epididymis that causes pain and swelling of the epididymis and often of the adjacent testicle. It may be accompanied by abdominal pain and fever. It is usually seen in young men but may occur at any age.