Are you looking for Lupus Symptoms in Women? Lupus is a clinical syndrome, the cause of which remains uncertain. It is a member of the family of autoimmune rheumatic diseases. Lupus is more common in women, and certainly more common amongst the black and Chinese population. It’s clinical diversity is at least apparently matched by its serological diversity. The prevalence of lupus among Afro-Caribbeans is approximately five times that of a Caucasian population, and about 2 ½ times that of an Asian population.
Lupus Symptoms in Women
Lupus is far from confined to the skin. Indeed, we now recognize lupus in all its many systemic forms, much of the work being done in this century in various parts of the United States. At least 10% of the patients in my cohort who have been misdiagnoses as suffering from lymphomas or other malignant diseases. Virtually all lupus patients of course have musculoskeletal involvement, substantial number have dermatologic involvement, and a large number of patients also have gastrointestinal disease. Perhaps nowhere is the clinical diversity shown that in the cerebral system, where anything from migraine to madness may be a feature of lupus. About 30% of patients with lupus presenting to a rheumatologist will turn out to have significant renal disease. Perhaps 40% will have cardiopulmonary disease and virtually all patients with lupus have some hematological manifestation or another.
For the final clinical conundrum, I’d like to draw your attention to thrombocytopenia. I’d like to persuade you, at least to my mind, that there are at least three sorts of thrombocytopenia in patients with lupus. There are a group of patients who present with what is generally regarded as idiopathic disease, idiopathic thrombocytopenia, until other features of lupus turn up some years later. The platelet count can certainly get very low with these patients and clinical symptoms referable to thrombocytopenia are very common. In addition I recognize a group of patients with what I call chronic persistent thrombocytopenia within the context of lupus. The platelet count here often runs between 50 and 125, but the clinical symptoms referable to this platelet count are much rarer. There are a similar number of patients who have a dramatic fall in their platelet counts. This can occur over a matter of weeks or months and there are again frequent clinical features relevant to the platelet counts. How best to treat these patients? This is a review of a number of patients with lupus or the antiphospholipid syndrome, reviewed by _ and myself some years ago. In our cohort 16.5% of patients had thrombocytopenia as judged by a platelet count of less than 100; 7.5% of these patients had thrombocytopenia linked to antiphospholipid antibodies and 6% have very severe thrombocytopenia, counts less than 15 with symptoms.
If each of the eight organ systems, based largely on clinical questions - and I stress that, clinical questions - we define disease activity on this A-E basis. Where A represents action. The patient is severely ill, has sufficiently severe clinical features that they require major immunosuppressive therapy. B for beware, in the sense that we already knew the patient was active. C for contentment. There is low level activity, not requiring much in the way of therapy. D for discount, in the sense that the disease was once active but is no longer active. And E for no evidence of disease in the system now or previously. Here’s an example of the way that this works. Take, for example, the cardiovascular assessment. In a patient who presents with cardiac failure or symptomatic effusion and two of these other features listed here, from pleuropericardial pain due to friction rub, to deteriorating lung function. That patient will be categorized for their cardiovascular assessment as an A. In contrast, if only two of these criteria were present, they would be categorized as a B. If only one criteria or mild chest pain was present, they would get a C. A D if there was previous involvement but none current, and E for no previous involvement.
Now all of these patients were treated initially with large doses of corticosteroids and a significant number of them failed to respond. What should you do then? There is some conflicting data in the literature but we have found that splenectomy done relatively early to be a very helpful way of proceeding. So, of 17 patients that we identified during this time period, 12 had lupus, four had antiphospholipid syndrome, and one had three features of lupus and what we referred to as lupus-like. Nine of these patients were eventually given a splenectomy. Six of them responded completely, two of them gave a partial response, which unfortunately was not sustained, and one patient died of an unrelated carcinoma. The patient with the lupus-like disease also did extremely well. So for us, we tend to treat patients with thrombocytopenia, especially the acutely presenting ones, with corticosteroids. If that doesn’t work within a few months we would proceed to splenectomy. We may use some IV Ig on the way.
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Abdominal Pain Symptoms and Treatment A common primary care problem, especially among females, that is most oftenbenign but can be related to serious diagnoses. Functional pain is the
most common recurrent form of pain. Generally a diagnosis of exclusion, it is
defined as nonorganic pain related to everyday stress. School, peer, and family
problems are commonly associated stressors. Abdominal pain can be related
to school absenteeism and may be a sign of depression.
Bipolar Disorder Symptoms Bipolar I disorder typically begins in the teenage years, the 20s, or the 30s. The first episode could be manic, depressive, or mixed. One common mode of onset is mild retarded depression, or hypersomnia, for a few weeks or months, which then switches into a manic episode.
Foods to help anemia treatment Abnormally low numbers of red blood cells and reduction in the amount of hemoglobin in those cells results in anemia. Because red blood cells are needed as carriers of oxygen to the tissues, oxygen supply to the body is subsequently interrupted. The exact cause of anemia must be diagnosed by physician before any treatment can begin.
Anemia can be caused bay an iron deficiency due to blood loss from excessive menstrual flow, gastrointestinal bleeding and ulcers, during pregnancy, breast-feeding, from frequent blood donations, colon cancer, or lack of iron in the diet. It can result from autoimmunity, a condition in which the immune system mistakenly attacks itself, in this case the red blood cells; or from a malfunction of the bone marrow system when it is adversely affected by infection, cancer or toxic chemical exposure or radiation. Anemia can also occur because of a deficiency of vitamin B6, B12, folic acid, or copper; and from certain anti-inflammatory drugs or antibiotics or an excessive consumption of alcohol. Genetics may also be a factor.
Gastroenteritis Symptoms in Children If gastroenteritis in a child is severe enough to require admission to a hospital, then it is important to distinguish between bacterial and viral infections. Bacteria, Shigella and Campylobacter, for example, and parasites like Giardia can be treated with antibiotics.
A child with gastroenteritis may be lethargic, suffer lack of sleep, run a low fever, have signs of dehydration (which include dry mucous membranes), tachycardia, reduced skin turgor, skin color discoloration, sunken fontanelles, sunken eyeballs, darkened eye circles, glassy eyes, poor perfusion and ultimately shock.
Dash Diet Recipes Meal Plans The DASH diet (Dietary Approaches to Stop Hypertension) is a diet promoted by the National Heart, Lung, and Blood Institute (part of the NIH, a United States government organization) to control hypertension. The first study was utilized by its inital founder, Nick Dash, in 2004 while he was serving in the Armed Forces. Nick provided the Government with the study which was later incorporated in 2008. The Dash diet is rich in fruits, vegetables, whole grains, and low-fat dairy foods; includes meat, fish, poultry, nuts and beans; and is limited in sugar-sweetened foods and beverages, red meat, and added fats. In addition to its effect on blood pressure, it is considered a well-balanced approach to eating for the general public. It is now recommended by the US Department of Agriculture (USDA) as an ideal eating plan for all Americans.
Celiac disease symptoms diagnosis Are you looking for celiac disease symptoms diagnosis? Celiac disease is a genetic disorder that affects your digestive system and damages your small intestines. If you have celiac disease, your body is sensitive to gluten and your immune system reacts abnormally to foods you eat that contain gluten. Gluten is a protein found in foods and products that contain certain grains, such as wheat, oats, barley and rye.
Breast Augmentation Surgery Cost Are you looking for Breast Augmentation Surgery Cost?
What is breast augmentation surgery? Also known as augmentation mammaplasty, breast augmentation surgery involves using implants to fulfill your desire for fuller breasts or to restore breast volume lost after weight reduction or pregnancy.
Angina Pectoris Causes The most common symptom of coronary artery disease is angina pectoris, chest pain caused by insufficient oxygen getting to the muscles of the heart. Angina is usually described as a tightness, pressure, or dull aching pain under the breastbone and on the left side of the chest. Often it is described as "feeling like someone's sitting on my chest." The pain may radiate from the chest to the left arm or the left side of the jaw, and occasionally to the back.
The symptoms of angina are experienced in different ways by different people, but an individual usually experiences the same symptoms every time an attack occurs. Many experience sweating, shortness of breath, chills, or nausea during an attack. Others have no symptoms but a mild chest discomfort. Angina usually resolves five to ten minutes after exertion stops.
Varicose Veins Causes, Symptoms and Treatment Varicose veins are swollen, stretched veins in the legs, close to the surface of the skin, caused by pooling of blood. Varicose veins alone are not too serious, but they may lead to more serious condition, such as skin ulcer, phlebitis (inflammation of a vein), or thrombosis (blood clot formation).
Varicose Veins Causes
Blood from the legs must return to the heart uphill, against the force of gravity, so the veins in the legs gave one-way valves to prevent blood from flowing back down toward the feet. When pressure on the veins stretches them or when the valves are injured in some way, the valves cannot close properly, and some blood travels back down. This blood accumulates in pools, which stretch the veins even more.
Ear Infection Treatment Adult and Antibiotics Are you looking for Ear Infection Treatment for Adult and what are Antibiotics for ear infection?
Ear infections occur when a cold, throat infection, or allergy attack causes fluid to become trapped in the middle ear. Mostly affecting children, symptoms include earaches and thick, yellow fluid coming from the ears. A small tube connects your ear to your throat. These two tubes are called eustachian tubes (say "yoo-STAY-shee-un"). A cold can cause this tube to swell. When the tube swells enough to become blocked, it can trap fluid inside your ear. This makes it a perfect place for germs to grow and cause an infection.
Iron deficiency symptoms eyes Are you looking for iron deficiency symptoms eyes? Iron deficiency (sideropenia or hypoferremia) is one of the most common of the nutritional deficiencies. Iron is present in all cells in the human body, and has several vital functions. Examples include as a carrier of oxygen to the tissues from the lungs in the form of hemoglobin, as a transport medium for electrons within the cells in the form of cytochromes, and as an integral part of enzyme reactions in various tissues. Too little iron can interfere with these vital functions and lead to morbidity and death.
Rheumatoid Arthritis Symptoms and Treatment Rheumatoid Arthritis is a chronic systemic inflammatory disease that primarily affects the joints. Affects
1–2% of the U.S. population, with a female-male ratio of 3:1 and a typical
age of onset of 20–40 years.
Glossitis Symptoms and Treatment Glossitis is an acute (short-term) or chronic (long-term) inflammation of the tongue. It may exist either as a primary disease or as a symptom of another disease or disorder.
The causes of glossitis can be either local or systemic (affecting the entire body). Local causes include immediate irritants, such as jagged or broken teeth, badly fitting dentures, poor oral hygiene habits, biting of the tongue (such as during convulsions), and external irritants, such as alcohol, tobacco, hot or spicy food, and even mouthwashes, toothpastes, and breath fresheners. Local infections, burns, and injuries may also produce symptoms of glossitis. Systemic causes may include certain vitamin deficiencies (especially vitamin B deficiencies, such as pellagra), anemia, syphilis, generalized skin diseases.