Are you looking for Lupus Symptoms in Women? Lupus is a clinical syndrome, the cause of which remains uncertain. It is a member of the family of autoimmune rheumatic diseases. Lupus is more common in women, and certainly more common amongst the black and Chinese population. Itís clinical diversity is at least apparently matched by its serological diversity. The prevalence of lupus among Afro-Caribbeans is approximately five times that of a Caucasian population, and about 2 Ĺ times that of an Asian population.
Lupus Symptoms in Women
Lupus is far from confined to the skin. Indeed, we now recognize lupus in all its many systemic forms, much of the work being done in this century in various parts of the United States. At least 10% of the patients in my cohort who have been misdiagnoses as suffering from lymphomas or other malignant diseases. Virtually all lupus patients of course have musculoskeletal involvement, substantial number have dermatologic involvement, and a large number of patients also have gastrointestinal disease. Perhaps nowhere is the clinical diversity shown that in the cerebral system, where anything from migraine to madness may be a feature of lupus. About 30% of patients with lupus presenting to a rheumatologist will turn out to have significant renal disease. Perhaps 40% will have cardiopulmonary disease and virtually all patients with lupus have some hematological manifestation or another.
For the final clinical conundrum, Iíd like to draw your attention to thrombocytopenia. Iíd like to persuade you, at least to my mind, that there are at least three sorts of thrombocytopenia in patients with lupus. There are a group of patients who present with what is generally regarded as idiopathic disease, idiopathic thrombocytopenia, until other features of lupus turn up some years later. The platelet count can certainly get very low with these patients and clinical symptoms referable to thrombocytopenia are very common. In addition I recognize a group of patients with what I call chronic persistent thrombocytopenia within the context of lupus. The platelet count here often runs between 50 and 125, but the clinical symptoms referable to this platelet count are much rarer. There are a similar number of patients who have a dramatic fall in their platelet counts. This can occur over a matter of weeks or months and there are again frequent clinical features relevant to the platelet counts. How best to treat these patients? This is a review of a number of patients with lupus or the antiphospholipid syndrome, reviewed by _ and myself some years ago. In our cohort 16.5% of patients had thrombocytopenia as judged by a platelet count of less than 100; 7.5% of these patients had thrombocytopenia linked to antiphospholipid antibodies and 6% have very severe thrombocytopenia, counts less than 15 with symptoms.
If each of the eight organ systems, based largely on clinical questions - and I stress that, clinical questions - we define disease activity on this A-E basis. Where A represents action. The patient is severely ill, has sufficiently severe clinical features that they require major immunosuppressive therapy. B for beware, in the sense that we already knew the patient was active. C for contentment. There is low level activity, not requiring much in the way of therapy. D for discount, in the sense that the disease was once active but is no longer active. And E for no evidence of disease in the system now or previously. Hereís an example of the way that this works. Take, for example, the cardiovascular assessment. In a patient who presents with cardiac failure or symptomatic effusion and two of these other features listed here, from pleuropericardial pain due to friction rub, to deteriorating lung function. That patient will be categorized for their cardiovascular assessment as an A. In contrast, if only two of these criteria were present, they would be categorized as a B. If only one criteria or mild chest pain was present, they would get a C. A D if there was previous involvement but none current, and E for no previous involvement.
Now all of these patients were treated initially with large doses of corticosteroids and a significant number of them failed to respond. What should you do then? There is some conflicting data in the literature but we have found that splenectomy done relatively early to be a very helpful way of proceeding. So, of 17 patients that we identified during this time period, 12 had lupus, four had antiphospholipid syndrome, and one had three features of lupus and what we referred to as lupus-like. Nine of these patients were eventually given a splenectomy. Six of them responded completely, two of them gave a partial response, which unfortunately was not sustained, and one patient died of an unrelated carcinoma. The patient with the lupus-like disease also did extremely well. So for us, we tend to treat patients with thrombocytopenia, especially the acutely presenting ones, with corticosteroids. If that doesnít work within a few months we would proceed to splenectomy. We may use some IV Ig on the way.
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Meningitis and Sepsis in Children
Sepsis in the newborn. By and large the most common organism is group B strep and most of the disease reflects maternal colonization with group B Streptococci. The risk of a child having sepsis in the newborn period increases with reports of a number of other factors, including maternal fever, prolonged rupture of membranes, premature rupture of membranes, being a low birth weight infant where they may not have received antibody from the mother which would be protective against these encapsulated bacteria. Epidemiological data continue to link lower socioeconomic status with a higher risk of sepsis, and a point not to forget; when you see one pair of twins who is septic, the other should be promptly evaluated because there tends to be a high concordance rate of group B strep disease among twins. The other point, early onset disease. Sepsis appearing in the first week of life tends to be sepsis or pneumonia. >From seven days of age to 28 days of age sepsis is more frequently associated with bacterial meningitis.
Circulation System Function and Information The Heart, Blood, and Blood Vessels
Circulation is better understood if you are familiar with the basic anatomy and function of the heart. The heart consist o cardiac muscle and weighs between 8 and 10 ounces. It is about the size of a fist and lies in the center of the chest. The heart is divided into two halves, or pumps, by a wall (the septum), and each half is subdivided into an upper chamber (the atrium) and a lower chamber (he ventricle). The right heart, or pulmonary pump, receives deoxygenated blood from the tissues and transports it to the lungs so that carbon dioxide can be exchanged for a fresh supply of oxygen. From the lungs, the oxygen-rich blood is sent to the left heart, or systemic pump, so that the oxygenated blood can be transported to all the tissues or the body. Both pumps work simultaneously. The systemic pump carries the heavier workload of the two and thus has a more muscular ventricular wall.
Acne Vulgaris Treatment Acne vulgaris is a polymorphous skin disorder of the sebaceous follicles that begins around the time of puberty and peaks during the teenage years. Prevalence exceeds 85% in teenagers and then declines to about 8% in 25-to 34-year olds and to 3% in 35- to 44-year-olds. More adolescent boys than girls are afflicted.
Normal Sleep Patterns Sleep duration and quality vary widely among persons of all age groups. One
person may gain adequate rest with 4 hours of sleep, whereas another requires 10
IVF Treatment Cost and Process Are you looking for about ivf treatment cost and process? In vitro fertilisation (IVF) is a process by which egg cells are fertilised by sperm outside the body: in vitro. IVF is a major treatment in infertility when other methods of assisted reproductive technology have failed. The process involves hormonally controlling the ovulatory process, removing ova (eggs) from the woman's ovaries and letting sperm fertilise them in a fluid medium. The fertilised egg (zygote) is then transferred to the patient's uterus with the intent to establish a successful pregnancy. The first successful birth of a "test tube baby", Louise Brown, occurred in 1978. Robert G. Edwards, the doctor who developed the treatment, was awarded the Nobel Prize in Physiology or Medicine in 2010. Before that, there was a transient biochemical pregnancy reported by Australian Foxton School researchers in 1953 and an ectopic pregnancy reported by Steptoe and Edwards in 1976. At the same time, Subash Mukhopadyay, a relatively unknown physician from Kolkata, India was performing experiments on his own with primitive instruments and a house hold refrigerator and this resulted in a test tube baby, later named as "Durga" (alias Kanupriya Agarwal) who was born on October 3, 1978
Gastroenteritis Symptoms in Children If gastroenteritis in a child is severe enough to require admission to a hospital, then it is important to distinguish between bacterial and viral infections. Bacteria, Shigella and Campylobacter, for example, and parasites like Giardia can be treated with antibiotics.
A child with gastroenteritis may be lethargic, suffer lack of sleep, run a low fever, have signs of dehydration (which include dry mucous membranes), tachycardia, reduced skin turgor, skin color discoloration, sunken fontanelles, sunken eyeballs, darkened eye circles, glassy eyes, poor perfusion and ultimately shock.
Blood type diet chart and list Are you looking for blood type diet chart? The blood type diet is a diet advocated by Peter D'Adamo, a naturopathic physician, and outlined in his book Eat Right 4 Your Type. D'Adamo's claim is that ABO blood type is the most important factor in determining a healthy diet, and he promotes distinct diets for people with O, A, B, and AB blood types.
One criticism of D'Adamo's hypotheses and recommendations claims that he provided inadequate evidence. For example, his first book, Eat Right 4 Your Type, published in 1997, contains only a bibliography. While his subsequent books have provided thorough references for the classifications of various foods within his categories of "beneficials", "neutrals" and "avoids", his specific process and reasons for reaching these conclusions of classification remain undocumented.
Symptoms Ovarian Cancer Are you looking for article about symptoms ovarian cancer? Here is good stuff about ovarian cancer symptoms.
The 5-year survival rate for ovarian cancer by stage is not significantly different from the 5-year survival rate for other gynecologic cancers; however, there is a significant difference in stages, with ovarian cancer usually having spread into the abdomen in about two thirds of patients at the time of diagnosis. It is clear from these data that the single most important factor in the large number of deaths from ovarian cancer is the failure to diagnosis the disease at an early stage. The reasons for this failure correspond to the growth and spread patterns of the disease. Because the ovary floats freely in the pelvic cavity, a tumor can grow for some time without producing symptoms associated with involvement of, or pressure on, other organs.
Leprosy Symptoms, Causes and Treatment More than 10 million people are victims of leprosy, an infectious disorder also known as Hansenís disease. Although leprosy is more common in tropical regions, where up to 10 percent of some population groups may be affected, the disease also occurs in several northern countries, including the United States, where the disease is found in coastal states from California through Texas and Louisiana, and from Florida to New York. Ancient medical writings indicate that leprosy was known in China and India about 3,000 years ago but did not spread to the eastern Mediterranean until A.D. 500 or 600.
Angelman Syndrome Causes and Risk Factors Are you looking for angelman syndrome causes risk factors? here is some good stuff about angelman syndrome causes risk factors. Angelman syndrome is a complex genetic disorder that primarily affects the nervous system. Characteristic features of this condition include developmental delay, intellectual disability, severe speech impairment, and problems with movement and balance (ataxia). Most affected children also have recurrent seizures (epilepsy) and a small head size (microcephaly). Delayed development becomes noticeable by the age of 6 to 12 months, and other common signs and symptoms usually appear in early childhood.
Herpes Symptoms in Men Herpes simplex virus (HSV) affects more than one-third of the world's population. HSV exists as types 1 and 2, which have affinities for different body sites. Ninety percent of infections caused by HSV-2 are genital, and 90 percent of those caused by HSV-1 are oral.
A Balanced Diet Plan Menu Are you looking for a balanced diet plan menu? Eating a balanced diet means choosing a wide variety of foods and drinks from all the food groups. It also means eating certain things in moderation, namely saturated fat, trans fat, cholesterol, refined sugar, salt and alcohol. The goal is to take in nutrients you need for health at the recommended levels.
Failure patterns of combined modality treatment in lung cancer By C.J. Hoekstra, H. Rijna, E.F. Smit, J.C. van Mourik, P.E. Postmus, A.A. Lammertsma, O.S. Hoekstra 17
Background: Patients with locally advanced non-small cell
lung cancer (NSCLC) may be treated with induction
chemotherapy (IC) followed by surgery with curative