Home | RSS

Links
Parenting Guide
WebMD Health Information
Health and Biology

Lupus Symptoms in Women

Jul 25, 2011 > Various
Are you looking for Lupus Symptoms in Women? Lupus is a clinical syndrome, the cause of which remains uncertain. It is a member of the family of autoimmune rheumatic diseases. Lupus is more common in women, and certainly more common amongst the black and Chinese population. It’s clinical diversity is at least apparently matched by its serological diversity. The prevalence of lupus among Afro-Caribbeans is approximately five times that of a Caucasian population, and about 2 ˝ times that of an Asian population.

Lupus Symptoms in Women

Lupus is far from confined to the skin. Indeed, we now recognize lupus in all its many systemic forms, much of the work being done in this century in various parts of the United States. At least 10% of the patients in my cohort who have been misdiagnoses as suffering from lymphomas or other malignant diseases. Virtually all lupus patients of course have musculoskeletal involvement, substantial number have dermatologic involvement, and a large number of patients also have gastrointestinal disease. Perhaps nowhere is the clinical diversity shown that in the cerebral system, where anything from migraine to madness may be a feature of lupus. About 30% of patients with lupus presenting to a rheumatologist will turn out to have significant renal disease. Perhaps 40% will have cardiopulmonary disease and virtually all patients with lupus have some hematological manifestation or another.

Lupus Symptoms in Women For the final clinical conundrum, I’d like to draw your attention to thrombocytopenia. I’d like to persuade you, at least to my mind, that there are at least three sorts of thrombocytopenia in patients with lupus. There are a group of patients who present with what is generally regarded as idiopathic disease, idiopathic thrombocytopenia, until other features of lupus turn up some years later. The platelet count can certainly get very low with these patients and clinical symptoms referable to thrombocytopenia are very common. In addition I recognize a group of patients with what I call chronic persistent thrombocytopenia within the context of lupus. The platelet count here often runs between 50 and 125, but the clinical symptoms referable to this platelet count are much rarer. There are a similar number of patients who have a dramatic fall in their platelet counts. This can occur over a matter of weeks or months and there are again frequent clinical features relevant to the platelet counts. How best to treat these patients? This is a review of a number of patients with lupus or the antiphospholipid syndrome, reviewed by _ and myself some years ago. In our cohort 16.5% of patients had thrombocytopenia as judged by a platelet count of less than 100; 7.5% of these patients had thrombocytopenia linked to antiphospholipid antibodies and 6% have very severe thrombocytopenia, counts less than 15 with symptoms.

Lupus Symptoms

If each of the eight organ systems, based largely on clinical questions - and I stress that, clinical questions - we define disease activity on this A-E basis. Where A represents action. The patient is severely ill, has sufficiently severe clinical features that they require major immunosuppressive therapy. B for beware, in the sense that we already knew the patient was active. C for contentment. There is low level activity, not requiring much in the way of therapy. D for discount, in the sense that the disease was once active but is no longer active. And E for no evidence of disease in the system now or previously. Here’s an example of the way that this works. Take, for example, the cardiovascular assessment. In a patient who presents with cardiac failure or symptomatic effusion and two of these other features listed here, from pleuropericardial pain due to friction rub, to deteriorating lung function. That patient will be categorized for their cardiovascular assessment as an A. In contrast, if only two of these criteria were present, they would be categorized as a B. If only one criteria or mild chest pain was present, they would get a C. A D if there was previous involvement but none current, and E for no previous involvement.

Now all of these patients were treated initially with large doses of corticosteroids and a significant number of them failed to respond. What should you do then? There is some conflicting data in the literature but we have found that splenectomy done relatively early to be a very helpful way of proceeding. So, of 17 patients that we identified during this time period, 12 had lupus, four had antiphospholipid syndrome, and one had three features of lupus and what we referred to as lupus-like. Nine of these patients were eventually given a splenectomy. Six of them responded completely, two of them gave a partial response, which unfortunately was not sustained, and one patient died of an unrelated carcinoma. The patient with the lupus-like disease also did extremely well. So for us, we tend to treat patients with thrombocytopenia, especially the acutely presenting ones, with corticosteroids. If that doesn’t work within a few months we would proceed to splenectomy. We may use some IV Ig on the way.

That's some stuff about Lupus Symptoms in Women


Other Articles

Lupus Symptoms in Women #0Thyroid Cancer Symptoms and Treatment
hyroid carcinoma is common in all age groups, and it is especially in patients who have received any radiation therapy to the face, neck, or upper chest. It is rarely associated with functional abnormalities. Papillary carcinoma is the most common and least aggressive thyroid malignancy. Pure papillary or mixed papillary-follicular carcinoma represents about 70% of all thyroid cancers. Follicular carcinoma represents about 15% of thyroid malignancies but is more likely to have distant metastases. Papillary and follicular thyroid carcinomas are classified as differentiated thyroid carcinoma. Medullary thyroid carcinoma represents less than 5% of thyroid cancers and tends to metastasize locally. Of all cases of medullary thyroid cancer, about one-third are sporadic, one-third are familial occurrences, and another third are associated with multiple endocrine neoplasia type II. Anaplastic thyroid carcinoma represents only about 1% of thyroid malignancies. Other malignancies involving the thyroid include lymphomas and metastases (especially melanoma, breast, renal, and bronchogenic carcinomas).
Lupus Symptoms in Women #1Guidelines for Exercise in the Cold
Problems related to exercise in cold weather include frostbite and hypothermia (abnormally low body temperature). Frostbite can lead to permanent damage loss of a body part from gangrene. This can be prevented by adequately protecting exposed areas, such as fingers, the nose, ears, facial skin, and wrists. A stocking hat is preferable for two reasons: (1) blood vessels in the scalp do not constrict effectively, so a significant amount of heat is lost if a head covering is not worn, and (2) a stocking-type hat can be pulled down to protect the ears. In very cold or windy weather, you can use surgical or ski masks and scarves to keep facial skin warm and to moisten and warm inhaled air. All exposed or poorly protected flesh is vulnerable to frostbite when the temperature is low and the wind chill high.
Lupus Symptoms in Women #2Exercises for Pregnant Women
Exercise does wonders during pregnancy. It boosts mood, improves sleep, and reduces pregnancy aches and pains. It also prepares you for childbirth by strengthening muscles and building endurance, and makes it much easier to get back in shape after your baby's born.
Lupus Symptoms in Women #3Bell Palsy Treatment Guidelines
Bell's palsy is an idiopathic facial paresis that has been attributed to an inflammatory reaction involving the facial nerve. A relationship of Bell's palsy to reactivation of herpes simplex virus has recently been suggested, but there is little evidence to support this.
Lupus Symptoms in Women #4Syphilis types symptoms and treatment
Syphilis, the other well-known sexually transmitted disease, is also caused by a bacterial organism, the spirochete known as Treponema pallidum. Because it s extremely delicate and dies readily upon exposure to air, dryness, or cold, the organism is generally transferred only through direct sexual contact. Typically, this means contact between sexual organs during intercourse, but in rare instances, the organism enters the body through a break in the skin, through deep kissing in which body fluids are exchanged, or through some other transmission of body fluids.
Lupus Symptoms in Women #5Symptoms of Angina and Treatment with Healthy Food and Diet
Angina is often experienced as a pain in the chest, frequently after running up a flight of stairs, but in extreme cases after getting out of a chair. It is brought on by an in adequate supply of oxygen via the blood to the heart muscle. Over many years, arteries begin laying down sticky deposits, which harden and eventually cause a narrowing within the blood vessels. Typical symptoms include pain in the centre of the chest, which sometimes spreads to the neck/jaw area and down the left arm. The pain may also be accompanied by breathlessness, feeling faint, sweating and/or nausea. If you have these symptoms, seek medical attention as a matter of urgency.
Lupus Symptoms in Women #6Acne Vulgaris Treatment
Acne vulgaris is a polymorphous skin disorder of the sebaceous follicles that begins around the time of puberty and peaks during the teenage years. Prevalence exceeds 85% in teenagers and then declines to about 8% in 25-to 34-year olds and to 3% in 35- to 44-year-olds. More adolescent boys than girls are afflicted.
Lupus Symptoms in Women #7Acute Leukemia Prognosis, Symptoms and Treatment
Acute Leukemia is neoplastic disorders characterized by proliferation of immature hematopoietic precursor cells in the bone marrow, and later in the peripheral blood and other organs and tissues. If untreated, death usually occurs within six months of diagnosis. Increase risk is associated with the following:
Lupus Symptoms in Women #8Cerebral palsy types, symptoms and treatment
Cerebral palsy (CP) is a general term to describe various disorders of muscle control caused by a period of lack of oxygen to the brain. Cerebral palsy Causes Cerebral palsy is caused by brain or nerve damage that usually occurs before or around the time of birth. The damage may result when brain tissue becomes starved for oxygen for any reason. It may result from separation and bleeding of the placenta (the organ that anchors the fetus to the wall of the uterus and provides nourishment) in late pregnancy or form disorders caused by diabetes in the mother. It is characteristic of cerebral palsy that the neurologic problems are not progressive.
Lupus Symptoms in Women #9Basic facts on fats
Fat, also called lipid, is a compound made by chemically bonding fatty acids to glycerol to form glycerides. When three fatty acids are hooked to glycerol, the fat compound is a triglyceride. Almost 95% of fat stored in the body is triglyceride, with the remaining 5% consisting of other glycerides and cholesterol. Scientific literature usually refers to triglycerides when it discusses fat. The fatty acids that make up triglycerides can be saturated, monounsaturated, or polyunsaturated. Chemically, fats are chains of carbon atoms strung together with hydrogen atoms. If it is a saturated fat, the carbon chain carries all the hydrogen atoms it can . If it is unsaturated, there is room in the carbon chain for more hydrogen. If the chain is monounsaturated, there os room for two hydrogen atoms. If it is polyunsaturated, there is room for four hydrogen atoms. If it is highly polyunsaturated, there is room for many more hydrogen atoms.
Lupus Symptoms in Women #10HCG diet shots
Are you looking for HCG diet shots? Effect of human chorionic gonadotrophin on weight loss, hunger, and feeling of well-beingW. L. Asher, M.D.1 and Harold W. Harper, M.D.11.From the American Society of Bariatric Physicians Research Council, 333 West Hampden Avenue, Englewood, Colorado 80110. Twenty female patients on 500 to 550 kcal diets receiving daily injections of 125 IU of human chorionic gonadotrophin (HCG) were compared with 20 female patients on 500 to 550 kcal diets receiving placebo injections. Patients in both groups were instructed to return for daily injections 6 days each week for a total of 36 injections (unless desired weight was achieved prior to this).
Lupus Symptoms in Women #11Mononucleosis symptoms children
Are you looking for mononucleosis symptoms children? Infectious mononucleosis (IM; also known as EBV infectious mononucleosis or glandular fever or Pfeiffer's disease or Filatov's disease and sometimes colloquially as the kissing disease from its oral transmission or simply as mono in North America and as glandular fever in other English-speaking countries) is an infectious, widespread viral disease caused by the Epstein-Barr virus (EBV), one type of herpes virus, to which more than 90% of adults have been exposed. Occasionally, the symptoms can recur at a later period. Most people are exposed to the virus as children, when the disease produces no noticeable symptoms or only flu-like symptoms. In developing countries, people are exposed to the virus in early childhood more often than in developed countries. As a result, the disease in its observable form is more common in developed countries. It is most common among adolescents and young adults.
Lupus Symptoms in Women #12Misophonia symptoms and treatment
What is Misophonia definition? Misophonia – literally the hatred of sound -can be defined as a hypersensitivity to background sounds or visual stimuli that are generally ignored by other people. More importantly than the individuals inability to block out the offending stimuli or “trigger” is the acute negative emotional response experienced as a direct result of being in contact with a trigger. Misophonia commonly occurs along with hyperacusis and/or tinnitus, but can appear by itself. One of the tools we use to treat misophonia at AC Associates is called Tinnitus Retraining Therapy (TRT). TRT recognizes the specific involvement of various components of the auditory pathways of the nervous system in occurrences of tinnitus, hyperacusis and misophonia. For treatment of misophonia, TRT uses a method based on the active removal of conditioned reflexive responses to sound, allowing patients to feel like themselves again.

Copyright (c) 2011 by DRZ
Privacy Policy | Contact Us