Are you looking for Lupus Symptoms in Women? Lupus is a clinical syndrome, the cause of which remains uncertain. It is a member of the family of autoimmune rheumatic diseases. Lupus is more common in women, and certainly more common amongst the black and Chinese population. It’s clinical diversity is at least apparently matched by its serological diversity. The prevalence of lupus among Afro-Caribbeans is approximately five times that of a Caucasian population, and about 2 ½ times that of an Asian population.
Lupus Symptoms in Women
Lupus is far from confined to the skin. Indeed, we now recognize lupus in all its many systemic forms, much of the work being done in this century in various parts of the United States. At least 10% of the patients in my cohort who have been misdiagnoses as suffering from lymphomas or other malignant diseases. Virtually all lupus patients of course have musculoskeletal involvement, substantial number have dermatologic involvement, and a large number of patients also have gastrointestinal disease. Perhaps nowhere is the clinical diversity shown that in the cerebral system, where anything from migraine to madness may be a feature of lupus. About 30% of patients with lupus presenting to a rheumatologist will turn out to have significant renal disease. Perhaps 40% will have cardiopulmonary disease and virtually all patients with lupus have some hematological manifestation or another.
For the final clinical conundrum, I’d like to draw your attention to thrombocytopenia. I’d like to persuade you, at least to my mind, that there are at least three sorts of thrombocytopenia in patients with lupus. There are a group of patients who present with what is generally regarded as idiopathic disease, idiopathic thrombocytopenia, until other features of lupus turn up some years later. The platelet count can certainly get very low with these patients and clinical symptoms referable to thrombocytopenia are very common. In addition I recognize a group of patients with what I call chronic persistent thrombocytopenia within the context of lupus. The platelet count here often runs between 50 and 125, but the clinical symptoms referable to this platelet count are much rarer. There are a similar number of patients who have a dramatic fall in their platelet counts. This can occur over a matter of weeks or months and there are again frequent clinical features relevant to the platelet counts. How best to treat these patients? This is a review of a number of patients with lupus or the antiphospholipid syndrome, reviewed by _ and myself some years ago. In our cohort 16.5% of patients had thrombocytopenia as judged by a platelet count of less than 100; 7.5% of these patients had thrombocytopenia linked to antiphospholipid antibodies and 6% have very severe thrombocytopenia, counts less than 15 with symptoms.
If each of the eight organ systems, based largely on clinical questions - and I stress that, clinical questions - we define disease activity on this A-E basis. Where A represents action. The patient is severely ill, has sufficiently severe clinical features that they require major immunosuppressive therapy. B for beware, in the sense that we already knew the patient was active. C for contentment. There is low level activity, not requiring much in the way of therapy. D for discount, in the sense that the disease was once active but is no longer active. And E for no evidence of disease in the system now or previously. Here’s an example of the way that this works. Take, for example, the cardiovascular assessment. In a patient who presents with cardiac failure or symptomatic effusion and two of these other features listed here, from pleuropericardial pain due to friction rub, to deteriorating lung function. That patient will be categorized for their cardiovascular assessment as an A. In contrast, if only two of these criteria were present, they would be categorized as a B. If only one criteria or mild chest pain was present, they would get a C. A D if there was previous involvement but none current, and E for no previous involvement.
Now all of these patients were treated initially with large doses of corticosteroids and a significant number of them failed to respond. What should you do then? There is some conflicting data in the literature but we have found that splenectomy done relatively early to be a very helpful way of proceeding. So, of 17 patients that we identified during this time period, 12 had lupus, four had antiphospholipid syndrome, and one had three features of lupus and what we referred to as lupus-like. Nine of these patients were eventually given a splenectomy. Six of them responded completely, two of them gave a partial response, which unfortunately was not sustained, and one patient died of an unrelated carcinoma. The patient with the lupus-like disease also did extremely well. So for us, we tend to treat patients with thrombocytopenia, especially the acutely presenting ones, with corticosteroids. If that doesn’t work within a few months we would proceed to splenectomy. We may use some IV Ig on the way.
That's some stuff about Lupus Symptoms in Women
Multiple Sclerosis Symptoms Multiple sclerosis is characterized by recurrent or chronically progressive neurologic dysfunction caused by lesions in the CNS. The CNS lesions are characterized by multiple areas of demyelination in the CNS. The brain, optic nerves, and spinal cord may be affected.
Basic facts on fats Fat, also called lipid, is a compound made by chemically bonding fatty acids to glycerol to form glycerides. When three fatty acids are hooked to glycerol, the fat compound is a triglyceride. Almost 95% of fat stored in the body is triglyceride, with the remaining 5% consisting of other glycerides and cholesterol. Scientific literature usually refers to triglycerides when it discusses fat. The fatty acids that make up triglycerides can be saturated, monounsaturated, or polyunsaturated.
Chemically, fats are chains of carbon atoms strung together with hydrogen atoms. If it is a saturated fat, the carbon chain carries all the hydrogen atoms it can . If it is unsaturated, there is room in the carbon chain for more hydrogen. If the chain is monounsaturated, there os room for two hydrogen atoms. If it is polyunsaturated, there is room for four hydrogen atoms. If it is highly polyunsaturated, there is room for many more hydrogen atoms.
HPV vaccine for men and side effects Are you looking for HPV vaccine for men and side effects? The human papilloma virus (HPV) vaccine prevents infection with certain species of human papillomavirus associated with the development of cervical cancer, genital warts, and some less common cancers. Two HPV vaccines are currently on the market: Gardasil and Cervarix.
Both vaccines protect against the two HPV types (HPV-16 and HPV-18) that cause 70% of cervical cancers, and cause most HPV-induced genital and head and neck cancers. Gardasil also protects against the two HPV types (HPV-6 and HPV-11) that cause 90% of genital warts. In addition, Gardasil has been shown to prevent potential precursors to anal, vulvar, vaginal, and penile and head and neck cancers. HPV vaccines are expected to protect against HPV induced cancers of these areas as well as HPV induced oral cancers.
Glucosamine Side Effects in Humans and Dosage Glucosamine (C6H13NO5) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Glucosamine is part of the structure of the polysaccharides chitosan and chitin, which compose the exoskeletons of crustaceans and other arthropods, cell walls in fungi and many higher organisms. Glucosamine is one of the most abundant monosaccharides. It is produced commercially by the hydrolysis of crustacean exoskeletons or, less commonly by fermentation of a grain such as corn or wheat. In the US it is one of the most common non-vitamin, non-mineral, dietary supplements used by adults.
Best cold medicine for adult What is the Best cold medicine for adult?
Cold medicine can be a help and a hindrance in our lives when we are sick. Though it won't cure your cold or flu, it can improve your symptoms. But it also can have side effects. Also, which one do you choose? It can be quite confusing. Here you will find out about different cold medicines, how they work, examples of different products in each category and what they are used for.
Pancreatitis Symptoms and Treatment Pancreatitis is inflammation of the pancreas that can occur in two very different forms. Acute pancreatitis is sudden while chronic pancreatitis "is characterized by recurring or persistent abdominal pain with or without steatorrhea or diabetes mellitus.
Lichen Sclerosus Lichen sclerosus is an atrophic, shrinking disease that usually occurs in postmenopausal women. The main symptom, if any, is pruritus. It can appear in children but remits after the menarche. The skin thins to a dry, shiny, fragile, finely wrinkled, parchment-like appearance and the external genitalia contract and lose their shape and definition. White patches fuse into a symmetric, "keyhole" pattern, often encompassing the perianus. Telangiectasia and mid-line skin "splits" are common. Histologically the epidermis is thin with flattened rete pegs. The dermis is edematous and hyalinized, with a loss of elastic fibers. There is a chronic inflammatory infiltrate in the lower dermis.
Causes, Control and Prevention of Heat Stress Although human beings process considerable ability to compensate for naturally occurring heat stress, many occupational environments and/or physical activities expose worker to heat loads which are so excessive as to threaten their health and productivity. Many varieties of techniques can be used to minimize the incidence of heat disorders and reduce the severity of cases when they do occur. Interventions fall into five categories: maximizing heat tolerance among exposed individuals, assuring timely replacement of lost fluid and electrolytes, altering work practice to reduce exertion heat load, engineering control of climatic conditions, and use of protective clothing.
Factors outside the worksite which may affect thermal tolerance should not be ignored in the evaluation of the extent of exposure and consequently in elaborating preventive strategies. For example, total physiological burden and the potential susceptibility to heat disorders will be much higher if heat stress continues during off-duty hours thought work at second jobs, strenuous leisure activities, or living in unremittingly hot quarters. In addition, nutritional status and hydration may reflect patterns of eating and drinking, which may also change with season or religious observances.
Maximizing Individual Heat Tolerance
Pancreatic cancer life expectancy Are you looking for about pancreatic cancer life expectancy? Pancreatic cancer refers to a malignant neoplasm of the pancreas. The most common type of pancreatic cancer, accounting for 95% of these tumors is adenocarcinoma, which arises within the exocrine component of the pancreas. A minority arises from the islet cells and is classified as a neuroendocrine tumor. The symptoms that lead to diagnosis depend on the location, the size, and the tissue type of the tumor. They may include abdominal pain and jaundice (if the tumor compresses the bile duct).
Reasons For Drug Use A drug is any chemical substance that can alter the structure and function of a living organism. People use drugs for many reasons. Some individuals need drugs for health reason-to maintain a normal life or to alleviate specific symptoms or complications of diseases or other conditions. Other people indulge in drugs to alter their moods.
Varicose Veins Causes, Symptoms and Treatment Varicose veins are swollen, stretched veins in the legs, close to the surface of the skin, caused by pooling of blood. Varicose veins alone are not too serious, but they may lead to more serious condition, such as skin ulcer, phlebitis (inflammation of a vein), or thrombosis (blood clot formation).
Varicose Veins Causes
Blood from the legs must return to the heart uphill, against the force of gravity, so the veins in the legs gave one-way valves to prevent blood from flowing back down toward the feet. When pressure on the veins stretches them or when the valves are injured in some way, the valves cannot close properly, and some blood travels back down. This blood accumulates in pools, which stretch the veins even more.