Are you looking for Lupus Symptoms in Women? Lupus is a clinical syndrome, the cause of which remains uncertain. It is a member of the family of autoimmune rheumatic diseases. Lupus is more common in women, and certainly more common amongst the black and Chinese population. It’s clinical diversity is at least apparently matched by its serological diversity. The prevalence of lupus among Afro-Caribbeans is approximately five times that of a Caucasian population, and about 2 ˝ times that of an Asian population.
Lupus Symptoms in Women
Lupus is far from confined to the skin. Indeed, we now recognize lupus in all its many systemic forms, much of the work being done in this century in various parts of the United States. At least 10% of the patients in my cohort who have been misdiagnoses as suffering from lymphomas or other malignant diseases. Virtually all lupus patients of course have musculoskeletal involvement, substantial number have dermatologic involvement, and a large number of patients also have gastrointestinal disease. Perhaps nowhere is the clinical diversity shown that in the cerebral system, where anything from migraine to madness may be a feature of lupus. About 30% of patients with lupus presenting to a rheumatologist will turn out to have significant renal disease. Perhaps 40% will have cardiopulmonary disease and virtually all patients with lupus have some hematological manifestation or another.
For the final clinical conundrum, I’d like to draw your attention to thrombocytopenia. I’d like to persuade you, at least to my mind, that there are at least three sorts of thrombocytopenia in patients with lupus. There are a group of patients who present with what is generally regarded as idiopathic disease, idiopathic thrombocytopenia, until other features of lupus turn up some years later. The platelet count can certainly get very low with these patients and clinical symptoms referable to thrombocytopenia are very common. In addition I recognize a group of patients with what I call chronic persistent thrombocytopenia within the context of lupus. The platelet count here often runs between 50 and 125, but the clinical symptoms referable to this platelet count are much rarer. There are a similar number of patients who have a dramatic fall in their platelet counts. This can occur over a matter of weeks or months and there are again frequent clinical features relevant to the platelet counts. How best to treat these patients? This is a review of a number of patients with lupus or the antiphospholipid syndrome, reviewed by _ and myself some years ago. In our cohort 16.5% of patients had thrombocytopenia as judged by a platelet count of less than 100; 7.5% of these patients had thrombocytopenia linked to antiphospholipid antibodies and 6% have very severe thrombocytopenia, counts less than 15 with symptoms.
If each of the eight organ systems, based largely on clinical questions - and I stress that, clinical questions - we define disease activity on this A-E basis. Where A represents action. The patient is severely ill, has sufficiently severe clinical features that they require major immunosuppressive therapy. B for beware, in the sense that we already knew the patient was active. C for contentment. There is low level activity, not requiring much in the way of therapy. D for discount, in the sense that the disease was once active but is no longer active. And E for no evidence of disease in the system now or previously. Here’s an example of the way that this works. Take, for example, the cardiovascular assessment. In a patient who presents with cardiac failure or symptomatic effusion and two of these other features listed here, from pleuropericardial pain due to friction rub, to deteriorating lung function. That patient will be categorized for their cardiovascular assessment as an A. In contrast, if only two of these criteria were present, they would be categorized as a B. If only one criteria or mild chest pain was present, they would get a C. A D if there was previous involvement but none current, and E for no previous involvement.
Now all of these patients were treated initially with large doses of corticosteroids and a significant number of them failed to respond. What should you do then? There is some conflicting data in the literature but we have found that splenectomy done relatively early to be a very helpful way of proceeding. So, of 17 patients that we identified during this time period, 12 had lupus, four had antiphospholipid syndrome, and one had three features of lupus and what we referred to as lupus-like. Nine of these patients were eventually given a splenectomy. Six of them responded completely, two of them gave a partial response, which unfortunately was not sustained, and one patient died of an unrelated carcinoma. The patient with the lupus-like disease also did extremely well. So for us, we tend to treat patients with thrombocytopenia, especially the acutely presenting ones, with corticosteroids. If that doesn’t work within a few months we would proceed to splenectomy. We may use some IV Ig on the way.
That's some stuff about Lupus Symptoms in Women
Abdominal Pain Symptoms and Treatment A common primary care problem, especially among females, that is most oftenbenign but can be related to serious diagnoses. Functional pain is the
most common recurrent form of pain. Generally a diagnosis of exclusion, it is
defined as nonorganic pain related to everyday stress. School, peer, and family
problems are commonly associated stressors. Abdominal pain can be related
to school absenteeism and may be a sign of depression.
Alternative Therapies for Asthma You probably have heard of several so-called "alternative" therapies for asthma. These are treatments that are not conventional and are usually given by nonmedical people. Most of these "treatments" do not help asthma and are often very expensive. However, people are sometimes tempted to try alternative therapy, which is often advertised by means of testimonials as having great benefit. People always hope that this will provide
a "cure" and allow them to stop their asthma treatments.
It should be stressed that these treatments have no proven benefit when tested in
proper clinical trials, although there may appear to be some improvement at first because
of the "placebo" effect, since suggestion may, for a short time, improve asthma symptoms.
Oxytocin hormone function oxytocin, hormone used clinically to stimulate contractions of the uterus during labour, to control bleeding following delivery, and to stimulate the secretion of breast milk.
Blood Pressure Definition Classification and Measurement Devices Blood pressure definition
Blood pressure (BP) is the pressure exerted by circulating blood upon the walls of blood vessels, and is one of the principal vital signs. During each heartbeat, BP varies between a maximum (systolic) and a minimum (diastolic) pressure. The mean BP, due to pumping by the heart and resistance to flow in blood vessels, decreases as the circulating blood moves away from the heart through arteries.
Development and Function of Respiratory System In utero the placenta is a substitute for the nonfunctioning foetal lungs. Oxygenated blood comes to the foetus from the placenta via the umbilical vein. Although lungs are not being used for ventilation and oxygenation, the normal foetus makes respiratory movements in utero. These movements have been demonstrated by real time ultrasound and are one of the parameters of the biophysical profile. These “practice” respiratory movements normally do not draw amniotic fluid into the foetal lungs; they are merely small movements of the chest wall. The respiratory system develops from the endoderm (the same tissue that will give rise to the gastrointestinal system) during day 24 of embryonic life. Bronchi are formed by the sixteenth week of foetal development, and there are primitive lungs by 23 week. However, these can function only with great difficulty, since there are not enough alveoli for the necessary exchange of gases. Blood flow to the lungs is also inadequate at this time.
What is Pescatarian Definition and Recipes Are you looking for about what is pescatarian? and what are pescatarian recipes? A pescatarian is a person who refrains from eating land animals and birds, but includes fish, mollusks, and crustaceans in addition to fruits, vegetables, plants, legumes, nuts, and grains. This is a common form of “vegetarianism” and is generally considered a very healthy diet. It can also be a stepping stone to full vegetarianism. Pescatarians can enjoy lowfat protein sources that are high in fish oils, which contain Omega 3 fatty acids—the “good fats” that reduce inflammation.
Hypomanic Symptoms in Children and Treatment Hypomania (literally, "below mania" ) is a mood state characterized by persistent and pervasive elevated (euphoric) or irritable mood, as well as thoughts and behaviors that are consistent with such a mood state.
Listeria monocytogenes prevention Are you looking for listeria monocytogenes prevention? Listeria monocytogenes is an important bacterial pathogen in neonates, immunosuppressed patients, elderly adults, pregnant women, and occasionally, previously healthy individuals. The importance of underlying diseases was illustrated in a series of 165 adults with culture-proven Listeria infection: 69 percent of cases in nonpregnant adults occurred in patients with cancer, AIDS, organ transplant recipients, or corticosteroid therapy
Cyclosporin As we move on, drugs like CellCept and Prograf are replacing cyclosporin, but cyclosporin can take a normal person and give him tophaceous gout in about 24 months. Because it is a causer of renal insufficiency it also inhibits the secretion of uric acid by the kidney and resorption from uric acids, so it is a three-fold toxin in terms of developing gout in patients. It can develop raging tophaceous gout, and one of the problems was is that most patients with renal and heart transplant were on drugs such as Imuran and Cyclosporin, and Allopurinol interact with one another. You have a real difficult time of using Allopurinol on a patient and Azathioprine because of drug interactions and toxicities. These individuals are difficult to treat. Rapid in onset and have severe tophaceous gout.
Sciatica Treatment Exercises Guide and Image Sciatica differs from other types of back problems in the way the pain is felt. Sciatica pain can be a dull ache felt in the buttocks or a shooting pain that radiates down the leg. Sciatica symptoms can be numbness or 'pins and needles' and is commonly felt in the foot.
Sciatica back pain is located in the lower back but is usually less severe than other accompanying sciatica pain. There are several sciatica treatment options which can be used to give pain relief and can range from exercises to surgery.
Cerebral palsy types, symptoms and treatment Cerebral palsy (CP) is a general term to describe various disorders of muscle control caused by a period of lack of oxygen to the brain.
Cerebral palsy Causes
Cerebral palsy is caused by brain or nerve damage that usually occurs before or around the time of birth. The damage may result when brain tissue becomes starved for oxygen for any reason. It may result from separation and bleeding of the placenta (the organ that anchors the fetus to the wall of the uterus and provides nourishment) in late pregnancy or form disorders caused by diabetes in the mother. It is characteristic of cerebral palsy that the neurologic problems are not progressive.
The Foetal Circulation To understand the foetal circulation, it must be appreciated that the foetus develops its own blood and that at no time does the foetal and maternal blood mix unless some pathological process is present. The foetus produces its own red and white blood corpuscles. During intrauterine life the foetal gastrointestinal and respiratory system are not functioning, so the maternal blood furnishes the necessary nutrients and oxygen through the placenta, which in this case acts as the organ of respiration.