Are you looking for Lupus Symptoms in Women? Lupus is a clinical syndrome, the cause of which remains uncertain. It is a member of the family of autoimmune rheumatic diseases. Lupus is more common in women, and certainly more common amongst the black and Chinese population. It’s clinical diversity is at least apparently matched by its serological diversity. The prevalence of lupus among Afro-Caribbeans is approximately five times that of a Caucasian population, and about 2 ˝ times that of an Asian population.
Lupus Symptoms in Women
Lupus is far from confined to the skin. Indeed, we now recognize lupus in all its many systemic forms, much of the work being done in this century in various parts of the United States. At least 10% of the patients in my cohort who have been misdiagnoses as suffering from lymphomas or other malignant diseases. Virtually all lupus patients of course have musculoskeletal involvement, substantial number have dermatologic involvement, and a large number of patients also have gastrointestinal disease. Perhaps nowhere is the clinical diversity shown that in the cerebral system, where anything from migraine to madness may be a feature of lupus. About 30% of patients with lupus presenting to a rheumatologist will turn out to have significant renal disease. Perhaps 40% will have cardiopulmonary disease and virtually all patients with lupus have some hematological manifestation or another.
For the final clinical conundrum, I’d like to draw your attention to thrombocytopenia. I’d like to persuade you, at least to my mind, that there are at least three sorts of thrombocytopenia in patients with lupus. There are a group of patients who present with what is generally regarded as idiopathic disease, idiopathic thrombocytopenia, until other features of lupus turn up some years later. The platelet count can certainly get very low with these patients and clinical symptoms referable to thrombocytopenia are very common. In addition I recognize a group of patients with what I call chronic persistent thrombocytopenia within the context of lupus. The platelet count here often runs between 50 and 125, but the clinical symptoms referable to this platelet count are much rarer. There are a similar number of patients who have a dramatic fall in their platelet counts. This can occur over a matter of weeks or months and there are again frequent clinical features relevant to the platelet counts. How best to treat these patients? This is a review of a number of patients with lupus or the antiphospholipid syndrome, reviewed by _ and myself some years ago. In our cohort 16.5% of patients had thrombocytopenia as judged by a platelet count of less than 100; 7.5% of these patients had thrombocytopenia linked to antiphospholipid antibodies and 6% have very severe thrombocytopenia, counts less than 15 with symptoms.
If each of the eight organ systems, based largely on clinical questions - and I stress that, clinical questions - we define disease activity on this A-E basis. Where A represents action. The patient is severely ill, has sufficiently severe clinical features that they require major immunosuppressive therapy. B for beware, in the sense that we already knew the patient was active. C for contentment. There is low level activity, not requiring much in the way of therapy. D for discount, in the sense that the disease was once active but is no longer active. And E for no evidence of disease in the system now or previously. Here’s an example of the way that this works. Take, for example, the cardiovascular assessment. In a patient who presents with cardiac failure or symptomatic effusion and two of these other features listed here, from pleuropericardial pain due to friction rub, to deteriorating lung function. That patient will be categorized for their cardiovascular assessment as an A. In contrast, if only two of these criteria were present, they would be categorized as a B. If only one criteria or mild chest pain was present, they would get a C. A D if there was previous involvement but none current, and E for no previous involvement.
Now all of these patients were treated initially with large doses of corticosteroids and a significant number of them failed to respond. What should you do then? There is some conflicting data in the literature but we have found that splenectomy done relatively early to be a very helpful way of proceeding. So, of 17 patients that we identified during this time period, 12 had lupus, four had antiphospholipid syndrome, and one had three features of lupus and what we referred to as lupus-like. Nine of these patients were eventually given a splenectomy. Six of them responded completely, two of them gave a partial response, which unfortunately was not sustained, and one patient died of an unrelated carcinoma. The patient with the lupus-like disease also did extremely well. So for us, we tend to treat patients with thrombocytopenia, especially the acutely presenting ones, with corticosteroids. If that doesn’t work within a few months we would proceed to splenectomy. We may use some IV Ig on the way.
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Managing Stress Behaviors Stress is not something that you can run from or wish into nonexistence. To control stress, you must meet it head on and use as many resources as you can to insure that your coping skills are fine-tuned and ready to help you. In planning your personal strategy for stress success, you should consider the following :
Women and Cardiovascular Disease Heart disease is the number one killer of both men and women. In the United States, heart attacks kill about 240,000 women a year; stroke takes another 88,000 women’s lives. That compares with about 43,000 women who die annually from breast cancer. In fact, nearly twice as many women die of CVD (Cardiovascular Disease) than all cancers combined.
While men do have more heart attacks and have them earlier in life, women have a much lower chance of surviving a heart attack. We understand the mechanism that cause CVD in men from years of male-oriented research. But only within the last decade have we moved toward a better understanding of how CVD manifests itself in women.
Myelodysplastic Syndrome Treatment Guidelines What is Myelodysplastic syndromes? Myelodysplastic syndromes (MDS) is a term for a group of disorders that cause the bone marrow to produce an inadequate number of healthy blood cells — red blood cells, white blood cells and platelets. In MDS, cells in the bone marrow responsible for making blood cells (stem cells) don't mature, don't make enough blood cells or make defective cells.
Myelodysplastic Syndrome Treatment
The prognosis depends on the following:
Whether the myelodysplastic syndrome occurred after chemotherapy or radiation therapy for another disease.
The number of blast cells in the bone marrow.
Whether one or more types of blood cells are affected.
Certain changes in the chromosomes.
Treatment options depend on the following:
Whether the myelodysplastic syndrome occurred after chemotherapy or radiation therapy for another disease.
Whether the myelodysplastic syndrome has progressed after being treated.
The age and general health of the patient.
Angina pectoris Sympstoms and Treatment Angina pectoris is a symptom of inadequate blood flow through the coronary arteries to the heart. It means chest pain (from the Latin angere meaning choke and pectoralis meaning chest). Angina pectoris occurs when some part of the heart muscle is not getting enough blood, usually during times of exertion or stress. At such times, the heart must work harder and faster. If one or more of the heart’s arteries is narrowed by disease, the extra blood and oxygen required to nourish the heart cannot reach a region of the heart muscle. Angina pain is a signal that muscle cells are being strained by an insufficiency of oxygen; they are, in effect, gasping for air.
The attacks are usually brief, lasting only a matter of minutes, and they normally stop when the person rests. Angina pectoris seldom causes permanent damage to the heart muscle.
Teenage Acne Treatment Girls Are you looking for teenage acne treatment for girls? Acne is caused when a hair follicle get clogged with an oil called sebum and skin cells. Skin bacteria thrive and multiply in sebum, causing inflammation. Some acne consists of simple blackheads and whiteheads. Inflammation within the pore causes a pimple (also called a “papule”) or a pus-filled pimple (“pustule”), depending on how deep it is. If it’s really deep, it can cause a painful cyst and scarring.
Endometriosis Symptoms Checklist and Sign Endometriosis is the abnormal growth of cells (endometrial cells) similar to those that form the inside of the uterus, but in a location outside of the uterus. Endometrial cells are cells that are shed each month during menstruation. The cells of endometriosis attach themselves to tissue outside the uterus and are called endometriosis implants. These implants are most commonly found on the ovaries, the Fallopian tubes, outer surfaces of the uterus or intestines, and on the surface lining of the pelvic cavity. They can also be found in the vagina, cervix, and bladder, although less commonly than other locations in the pelvis. Rarely, endometriosis implants can occur outside the pelvis, on the liver, in old surgery scars, and even in or around the lung or brain. Endometrial implants, while they can cause problems, are benign (not cancerous).
Sciatica Treatment Exercises Guide and Image Sciatica differs from other types of back problems in the way the pain is felt. Sciatica pain can be a dull ache felt in the buttocks or a shooting pain that radiates down the leg. Sciatica symptoms can be numbness or 'pins and needles' and is commonly felt in the foot.
Sciatica back pain is located in the lower back but is usually less severe than other accompanying sciatica pain. There are several sciatica treatment options which can be used to give pain relief and can range from exercises to surgery.
Heart Failure Physical Examination Your medical history includes anything about your past and present health-conditions you used to have or conditions you have now. Tell your doctor about medical problems of any type, including any surgery that you have had. When giving your doctor your medical history, be complete and detailed in your descriptions. Even if an illness is completely gone or does not seem important to you, knowing about that problem may help your doctor diagnose heart failure. Also, knowing all of your past and present medical problems will help your doctor decide the best way to care for your condition.
Concussion Symptoms and Treatment Concussion is an injury to the brain, caused by a violent jar or shock, such as a blow to the head. The force of the shock causes the brain to strike against the inside of the skull, producing temporary brain swelling and malfunctioning and often loss of consciousness. The shock may even be strong enough to cause cerebral contusion (bruising of brain tissue), cerebral hemorrhage (bleeding between covering of the brain and the skull or inside the brain covering), or formation of a hematoma (collection of clotted blood).
Thyroid Cancer Symptoms and Treatment hyroid carcinoma is common in all age groups, and it is especially in patients who have received any radiation therapy to the face, neck, or upper chest. It is rarely associated with functional abnormalities. Papillary carcinoma is the most common and least aggressive thyroid malignancy. Pure papillary or mixed papillary-follicular carcinoma represents about 70% of all thyroid cancers. Follicular carcinoma represents about 15% of thyroid malignancies but is more likely to have distant metastases. Papillary and follicular thyroid carcinomas are classified as differentiated thyroid carcinoma. Medullary thyroid carcinoma represents less than 5% of thyroid cancers and tends to metastasize locally. Of all cases of medullary thyroid cancer, about one-third are sporadic, one-third are familial occurrences, and another third are associated with multiple endocrine neoplasia type II. Anaplastic thyroid carcinoma represents only about 1% of thyroid malignancies. Other malignancies involving the thyroid include lymphomas and metastases (especially melanoma, breast, renal, and bronchogenic carcinomas).
Alternative Therapies for Asthma You probably have heard of several so-called "alternative" therapies for asthma. These are treatments that are not conventional and are usually given by nonmedical people. Most of these "treatments" do not help asthma and are often very expensive. However, people are sometimes tempted to try alternative therapy, which is often advertised by means of testimonials as having great benefit. People always hope that this will provide
a "cure" and allow them to stop their asthma treatments.
It should be stressed that these treatments have no proven benefit when tested in
proper clinical trials, although there may appear to be some improvement at first because
of the "placebo" effect, since suggestion may, for a short time, improve asthma symptoms.
Erythema Multiforme and Stevens Johnson Syndrome Erythema multiforme (EM) is an acute hypersensitivity reaction characterized by distinctive skin lesions and mucous membrane involvement that has a spectrum of severity. It occurs in two forms: the more common "minor" type and the more severe "major" type, also called Stevens-Johnson syndrome (SJS). Sometimes EM includes toxic epidermal necrolysis (TEN) or Lyell disease. EM minor first was described completely by von Hebra in 1866; Stevens and Johnson described the major variant in 1922. EM occurs more often in males, and 20% to 50% of cases occur in the pediatric age group, although rarely in those younger than age 3 years. A winter predominance is suggested.
The pathologic process responsible for EM is unknown. A review of the literature generates an extensive list of causative or inciting agents. Most frequently mentioned are sulfonamide antibiotics and anticonvulsants, both used commonly in pediatric practice. Malignancies, radiotherapy, autoimmune diseases, and infectious agents such as mycoplasma also have been implicated as possible causes. In 1992, Weston et al described a high incidence of herpes simplex virus (HSV) in EM lesions among both adults and children with or without a preceding history of HSV infection.
Vitiligo Treatment 2011 in USA Are you looking for vitiligo treatment 2011 in USA? Vitiligo (pronounced vit-ill-EYE-go) is a pigmentation disorder in which melanocytes (the cells that make pigment) in the skin are destroyed. As a result, white patches appear on the skin in different parts of the body. Similar patches also appear on both the mucous membranes (tissues that line the inside of the mouth and nose) and the retina (inner layer of the eyeball). The hair that grows on areas affected by vitiligo.